Tim3 CHO-K1 Cell Line

Description Tim3 CHO-K1 Cell Line T cell immunoglobulin mucin-3 (TIM3) is a member of the T-cell Immunoglobulin- and Mucin-domain-containing family of type I membrane glycoproteins. These proteins regulate autoimmune and allergic disease. TIM3 selectively expresses on Th1 cells and interacts with galectin-9. It negatively regulates Th1 responses and affects macrophage activation. The 280 amino acid mature human TIM3 contains a V-type Ig-like domain with multiple polymorphisms, followed by a mucin-like domain in the 171 amino acid extracellular region. The region shares 60% amino acid identity with mouse TIM3 ECD. Cells Online offers Tim3 CHO-K1 Cell Line for research in immune checkpoints and related drug discovery.